Japan approves Alzheimer’s blood test kit

Japan has approved a blood test kit to diagnose Alzheimer’s disease, its manufacturer announced on Thursday, a rare advance in tackling a condition that affects tens of millions worldwide.

Sysmex Corporation said it was now working to get the kit, which measures the accumulation of a protein that is a marker for the disease, to market “as soon as possible”.

Existing methods of diagnosing Alzheimer’s are expensive and medically intrusive, often involving a brain scan or spinal tap.

“Sysmex has been developing a technology to more quickly and readily identify the accumulation of (amyloid beta) in the brain in order to solve issues in the diagnosis of Alzheimer’s disease,” the company said.

“Unlike conventional testing methods… (the kit) allows testing with blood, thus reducing the physical, emotional, and financial burden on patients,” it added.

The Alzheimer’s Association, a US-based group, says “an urgent need exists for simple, inexpensive, non-invasive and easily available diagnostic tools such as blood tests to diagnose the disease”.

“In the future, they are very likely to revolutionise the diagnostic process for Alzheimer’s and all other dementia,” the group says on its website.

Last month, data showed a new drug called lecanemab slowed cognitive decline in Alzheimer’s patients by 27 percent across an 18-month period.

The data also revealed adverse effects including brain bleeds and swelling, but was largely hailed as offering a “real treatment option” for those with the degenerative cognitive disease.

In Alzheimer’s disease, two key proteins, tau and amyloid beta, build up into tangles and plaques, known together as aggregates, which cause brain cells to die and lead to brain shrinkage.

© Agence France-Presse

Business and consumers hamper climate fight: report

Corporations and consumers are the main obstacle to the emissions cuts needed to keep global warming to the 1.5-degree Celsius limit, researchers said Wednesday, adding that “positive signs” in other areas are not yet enough to meet climate goals.

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